IONIC LIQUID FORMS OF THE ANTIMALARIAL LUMEFANTRINE IN COMBINATION WITH LFCS TYPE IIIB LIPID-BASED FORMULATIONS PREFERENTIALLY INCREASE LIPID SOLUBILITY, IN VITRO SOLUBILIZATION BEHAVIOR AND IN VIVO EXPOSURE

Lipid based formulations (LBFs) are commonly employed to enhance the absorption of highly lipophilic, poorly water-soluble drugs.However, the utility of LBFs can be limited by low drug solubility in the formulation.Isolation of ionizable drugs as low melting, lipophilic salts Shower Bomb or ionic liquids (ILs) provides one means to enhance drug sol

In this paper, we propose a sophisticated battery model for vanadium redox flow batteries (VRFBs), which are a promising energy storage technology due to their design flexibility, low manufacturing costs on a large scale, indefinite lifetime, and recyclable electrolytes.Primarily, fluid distribution is analysed using computational fluid dynamics (C

Germline development in vivo is dependent on the environment formed by somatic cells and the differentiation cues they provide; hence, the impact of local factors is highly relevant to the production of sperm.Knowledge of how somatic and germline cells interact is central to achieving biomedical goals relating to restoring, preserving or restrictin